ʻO ka neuroblastoma kekahi o nā kuhumu maʻamau o ka pūpū pūpū i nā keiki, aʻo ia ka hopena o kāna mea aloha. Hoʻomaka ka uluʻana o ka'ōpū i loko o ka manawa intrauterine, i ka wā e hele ai nā pūnaewele maʻemaʻe i ka māliala maikaʻi, nā'aleʻa a me nā wahi'ē aʻe.
Ua hanaʻia ka pronoosis o neuroblastoma ma muli o kaʻikepili e like me: ke kau makahiki o ke keiki, ke kaʻina kahi i hanaʻia ai ka hōʻailona, a me nā hiʻohiʻona histological o nā pūnaewele maikaʻi. Ke pili nei kēia mauʻikepili i nā kumu pilikia. He mea nui e hoʻomaopopo i nā keiki me ka liʻiliʻi liʻiliʻi a kūponoʻole i ka manawa e ola hou ai, akā naʻe, hiki i nā poʻe maʻi me ka loiloi nui, ma muli o ka hōʻailona, ke kūlana liʻiliʻi o ke ola. ʻO nāʻike hou aku e pili ana i nā kumu, nā hōʻailona a me ka mālamaʻana i nā neuroblastoma i loko o nā keiki heluhelu i loko o kā mākou puke.
Neuroblastoma - Nā kumu
Me ka lōʻihi o ka noiʻiʻana,ʻaʻole i loaʻa i kahiʻepekema kekahi kumu kūpono o ka uluʻana o neuroblastoma. Eia kekahi,ʻaʻole i hiki ke hoʻomaopopo i nāʻano i hiki ke hoʻopili i konaʻike.
ʻOiaʻiʻo, aia he mau koho, akā naʻe,ʻaʻohe mea hōʻike. No laila, no ka hapanui,ʻikeʻia ke neuroblastoma i loko o nā keiki i loko o kaʻohana iʻike muaʻia i ka maʻi pōʻino. Akā i kēlā me kēia makahiki, ma ka honua nei, he awelika o 1-2% o nā hihia i hikiʻole ai i nā mākua a me nāʻohana pili keʻaʻa i kēia maʻi.
I kēia manawa, ke ninaninauʻia nei ka genome o nā maʻi me ka neuroblastomaʻohana no ka heluʻana i kahi gene (aiʻole kekahi mau gen), kahi hoʻololi, kahi paha e hoʻoulu ai i kēia ulu.
ʻO Neuroblastoma i nā keiki - nā hōʻailona
Nā hōʻailona o ke neuroblastoma ma nā keiki e pili ana i ka wahi mua o ka'ōpū a me ke alo a me ka halaʻole o nā metastases. ʻO nā hōʻailona "Classic" o ke neuroblastoma i loko o nā keiki: ke kaumaha o ka'ōpū, ka luaʻiʻana , ka poho kaumaha, kaʻai, ka luhi a me kaʻeha iwi. ʻO keʻano o ka hanu haʻahaʻa , a me ka maʻi diarrhea he mea maʻamau.
Ma muli o ka loaʻaʻana o nā maʻi he 50% o nā maʻi i ke kauka i ka hopena o ka maʻi,ʻo nā hōʻailona o ka maʻi ma kēia mau hihia e hāʻawiʻia ana e ka hōʻinoʻana o nā'ōpū kahi e kau ai nā maʻi kino. ʻO kēia mau mea kēia heʻeha iwi, ke kīnāʻole a me ka hoʻomauʻana i ke kuni, ka'ākau a me kaʻehaʻana i nā maka.
Aia ka maʻi i loko o ka umauma, hiki iā ia ke hana i ka maʻi maʻiʻo Claude-Bernard-Horner. ʻO ka hoʻolālāʻekolu o Horner,ʻo ia: kahi i hanaʻia o ka'ōpū, hoʻopiʻiʻia o ka haumana a me kahiʻoi loa o ka maka. Ma kahi maʻi pilikino he heterochromia - kahiʻano'ē aʻe o ka iris (e like paha me ka maka'ōmaʻomaʻo, a me kekahiʻano uliuli).
Eia kekahi, hiki i nā mākua o ke keiki maʻi ke nīnau i ke kauka no kekahi meaʻokoʻa loa - e like paha, he naha. Ma mua o ka huli houʻana, ua hōʻikeʻiaʻo ke kumu i lilo ai i kaʻeha o nā iwi, he mea ia.
Neuroblastoma - ka lāʻau
Hoʻomaʻoʻia o ke neuroblastoma i nohoʻia,ʻo ia hoʻi, he koko e pili ana i nā palena aʻaʻole no kekahi mea e hana ai. Ma hope o ka hoʻokuʻuʻiaʻana o ka hoʻonaʻauao, pono ka mana ola o ke keiki.
Akā i nā hihia i ka wā i mālamaʻia ai ka tumo e hāʻawi ana i nā metastases, ma waho aʻe o ka weheʻana i ka pilina ma mua o ka neuroblastoma,
Neuroblastoma - hoʻihoʻi
ʻO ka pōʻino, e like me ke kanikalē, hiki i nā neuroblastoma ke hāʻawi i nā kuʻi.
ʻO ka wānana i nāʻano likeʻole, heʻano likeʻole ia:
- ʻO ka hoʻi houʻana o kahi pālākiō (kahi o ka tumu hou) heʻano kūpono kūpono, no ka mea, hiki ke weheʻia i kahiʻoihana;
- i nā maʻi me kahi kāʻili hoʻi o ka hoʻihoʻiʻana, ponoʻole ka pronostic for life, no ka mea he paʻakikī ke mālama.