ʻO nā kauka lapaʻau hōʻailona hormone no ka manawa kahiko, akā me kāna kōkua, ua aʻo lākou eʻike i kekahi mau maʻi o ka'ōnaehana hānau, e hoʻoholo i ka wahine a me ka wānana i ka hoʻomakaʻana o ka maleopause. ʻO ka mea maʻamau,ʻo ka hōʻuluʻuluʻana i ka AMG e kauʻia e ke kaukahonua-endocrinologist i ka manawa mua o ka mālamaʻoleʻana i ka maʻiʻole me ke kōkua o nā kākoʻo hana i kākoʻoʻia (IVF, insemination artificial). ʻO ka high antimulylrov he hormone - he hōʻailona weliweli, e kamaʻilio ana no ka hikiʻana o nā maʻi kūikawā.
AMG i nā kāne a me nā wāhine
ʻO ka hormone o Antimiller (AMG) he glycoprotein pili i nā mea ulu. Hoʻomaka ka ulu o kēia mea i ka manawa o ka uluʻana o ka hānai: ma nā keiki e hiki mai ana - ma 7-8 wiki, a me nā kaikamahine i ka wā e hiki mai ana - ma kahi o 32-36 wiki o ke kōhua.ʻO kēia hormone ke kuleana no ka hoʻokumuʻana i ka'ōnaehana hānau kāne: ma lalo o ka mana o AMG, he hopena o ka embryo asexual (ka hoʻololi hope) o nā leka Mullerian - nā kumuhana o ka'ōpū o ka wā e hiki mai ana a me nā pullopola tubes. Ma hope o ka hānauʻana o nā keikikāne i ke kino, e hoʻomauʻia ka hormone ma nāʻano nui e nā pūmero Sertoli, a me ka hoʻomakaʻana o ka'ōpiopio e hoʻoemi nuiʻia ke kiʻekiʻe o ka hormone antimulylerovo.
Mālama AMG nā wāhine i nā pūnaewele ovarylosa ovary mai ka lāʻekolu o ka'ōpū ma mua o ka hoʻomakaʻana o ka minuke. I ka hoʻohālikelikeʻana me nā kāne,ʻo ka mea nui o ka hormone antimulylrovaya i loko o ke koko o ka wahine nāwaliwali, he haʻahaʻa loa ia, a ma hope o ka'ōpiopioʻana, e emi iho ana ke kiʻekiʻe o ka AMH. No ke aha mai kēia hana?
ʻO ka maʻamau,ʻo kēlā me kēia wahine i ka hānauʻana, he hua huaʻo ia, a me ka hōʻeaʻana o ka maʻemaʻe mua, e hoʻopauʻia i ka manopause. I loko o ka manawa haʻalulu, e ulu koke nā hanu i ka manawa hoʻokahi ma ka'ōpiopio, aʻo kekahi o ia (keu) e lilo i manu i oʻo. I kekahi manawa o ka hoʻouluʻana o nā pūlū pūmū, ua huaʻia kahi hormone antimuteler e mālama i ka uluʻana o nā follicles. Uaʻike nā kānakaʻepekema e hoʻopili pololeiʻia ke kiʻekiʻe o AMG me ka helu o nā hua kūpono. No laila, me ke kōkuaʻana o ke ATM, hiki i kekahi ke hoʻomaopopo i ka hoʻomahaʻana o ka wahine o ka wahine a me ka huki i nā manaʻo e pili ana i ka hoʻomakaʻana o ka maleopause.
Hoʻopiʻiʻia ka hormone - nā kumu
ʻO ka maʻamau ka nui o ka hormone antimulylerovo i loko o nā kāne 0.29-5,98 ng / ml, no ka mea maʻamau i kēia hōʻailona he like kēia me 1-2.5 ng / ml. ʻOiaʻiʻo, he hapa iki liʻiliʻi mai ka papa maʻamau. Eia kekahi laʻana, ma kahi pāʻani hormone anti-Muller a hiki i ka 3 ng / mg,ʻaʻole pono e hopohopo. Eia naʻe, i ka nui o nā wāhine antimulylerov ua nui ka hoʻonuiʻana o ka hormone:ʻo ka nui o ka AGM he 5-6, a 9 mau w / ml. He aha ke kumu o ia mau hōʻailona?
Uaʻike nā kauka i ka hormone hōʻailona wahine ma luna o ka maʻamau e pili ana i ka hikiʻana o nā ovary polycystic, a me kahi pūpū cellulosa o ke ovary. Eia hou, hiki i kahi AMG kiʻekiʻe ke kuhikuhi i ka endocrine normogonadotropic (anovulatory) infertility aiʻole ka lōʻihi o ka uluʻana i ka wahine. ʻO ia ma luna o ka mea maʻamau
I nā kāne,ʻo ka nui o ka hormone antimuller e'ōlelo ana no ke cryptorchidism (kahi o nā testes ma waho o ka pahu), hoʻolōʻihi i ka uluʻana i ka wahine, nā pilikia i ka hanaʻana o nā androgens a me nā maʻi'ē aʻe o ka'ōnaehana hānau.
Eia naʻe,ʻaʻole ka AMG kiʻekiʻe mau loa e hōʻike i ka hikiʻana o nā maʻi. I kekahi manawa ua nui ka mana o ka mea maʻi i nā hopena o ka aʻoʻana: pilikia, nā maʻi nui, nā haʻuki ikaika e pā i ka kiʻekiʻe o ka hormone i loko o ke koko. No laila,ʻekolu lā ma mua o ka hōʻuluʻulu manaʻoʻana, pono e alakaʻi i kahi noho maluhia, e pale i ka hōʻehaʻe a me ka paleʻana i nā hanaʻino inā hiki.