ʻO ke kumu nui o ka puʻuwai o ka naʻau , ka hahau a me nā meaʻeha o nā kīʻaha koko he atherosclerosis. ʻO ka mea nui i ka hoʻomohalaʻana o nā maʻi pilikino e pāʻaniʻia e ka cholesterol (alcool lipophilic), a waihoʻia nā kinikona i nā paia o nāʻene a me nā capillaries i keʻano o ka pā. Pono e hoʻonuiʻia kona kukū no ka hana a me ka mālamaʻana i ke atherosclerosis.
Nā Statins - he aha ia?
ʻO ka hapanui o ka poʻe i loaʻa i nā maʻi o ka maʻi kalapona eʻike i nā lāʻau lipid-downering i'ōleloʻia e like me nā lāʻau lapaʻau kūpono a maikaʻi loa e ho'ēmi i ka cholesterol. ʻAʻole kēia he hōʻoiaʻoiaʻiʻo. No kaʻike maopopo i keʻano o nā'enela, he mea nui eʻike i keʻano o ke kūkuluʻana a me ka holoʻana o ka waiʻona lipophilic, kona kumu a me kāna hana.
Hiki ke hoʻopiliʻia ka Cholesterol i loko o ke kino, a komo i waho ma waho, e like me ka meaʻai. Pono kēia mea ulu no:
- keʻano o nā meaola o ka lāʻau corticosteroids a me nā hormones wahine;
- ka palekana o nā erythrocytes mai nā poisons hemolytic;
- ke kaʻina hana o ke kamera pono;
- ka hana 'ana o ka wailele a me nā huamaʻi o ka hui D;
- ke hoʻomauʻiaʻana o ka membrane plasma.
Hiki i nā kino o ke kino ke hoʻololi i nā palekana - lipoproteins. Hoʻokani lākou i keʻano o ka laweʻana i nā meaola o ka cholesterol mai ke akepaʻa i nā mea a me ke kua. Nā Mokuna e pale i ka hanaʻana o nā enzymes i mua o ke kūʻana o lipoproteins. Ma muli o kēia, e ho'ēmi ana ka nui o ka cholesterol i ka paʻakai o ka mea, a piʻi ka nui o kaʻoihana o ke kaʻa. ʻO ka hopena, ua hoʻemi maikaʻiʻia kaʻawaʻawa lipophilic i loko o ke kino. I ka manawa like,ʻo nā lāʻau lapaʻau e noʻonoʻoʻia ana e pili ana i ka paleʻana i nā mea momona a me nā pāpale i loko o nā moku.
ʻO nā kūlana mai ka cholesterol maikaʻi a maikaʻi
ʻO nā hua'ōlelo lipid-downering kūpono loa ka hopena maikaʻiʻole, no laila ua kapu loa lākou e koho a lawe i kā lākou iho. Hoʻonohonoho ponoʻia nā kumukūʻai inā he hōʻike pololei no ko lākou hoʻohana. I ka hapanui o nā hihia, hiki ke hoʻemiʻia ka hoʻouluʻana o ka cholesterol ma kahi'ē aʻe a maikaʻi. ʻO kēia ka hoʻoponoponoʻana i ka meaʻai, ka hōʻoleʻana i nā hanaʻino, ka piʻiʻana i ka pae o ka hoʻolālā kino a me ka hoʻohālikelikeʻana i ka māhele o ka hana a me ka hoʻomaha.
He maikaʻi nā kalana mai ka cholesterol
ʻO nā lāʻau'apaʻau i kākauʻia he mea ia wale nō ka koho no ka lapaʻana a me ka mālamaʻana i nā maʻi o ka maʻiʻoi loa o ka maʻi, ināʻaʻole i lawa ka lawaʻana o nā lāʻau lapaʻau. ʻO nā pono o statins nā mea i lalo:
- ua hōʻemi i ka hopena o ka hāpū o ka naʻau;
- ka paleʻana i nā hopena ischemic e pili ana , nā hahau;
- ke hoʻomau nei i ka holomua a me ka paleʻana i ka uluʻana o ke atherosclerosis;
- ke hoʻomauʻana i ka hana o ka naʻau e kū'ē i ka angina, maʻi maʻi;
- hoʻopakele i nā hōʻailona o ka maʻi maʻi;
- ka poho kaumaha me ka momona;
- ka nāwaliwali o nā papahana inflammatory ma nā pāpaʻi pāpuni;
- ka hoʻouluʻana o nā plaque atherosclerotic ;
- ka hoʻopaʻiʻana i ke koko, ka mea e ho'ēmi ai i ka hopena o ke koko;
- ka hoʻomauʻana i nā kaʻina hana metabolic i loko o ke kino;
- ka palaʻau.
ʻO nā kaomi mai ka cholesterol nā lāʻau lapaʻau maikaʻi loa a palekana no ka holoʻana i ka hoʻoponopono hou ma hope o:
- pupule;
- ka hōʻeuʻeu ischemic;
- ke kāʻeiʻokoʻa;
- 'ā'ōpila;
- 'eeʻole i ke kīnā;
- ka pulmonary embolism.
Nā hopena o nāʻano
ʻO ka pilikia nui o ka hoʻohanaʻana i kēia mau lāʻau,ʻo ia ka hopena o nā hopena pili. I ka likeʻana me ka emiʻana o ka hana lipoproteins, ua hoʻoihoʻia nā lāʻauʻaina i ka hana o coenzymes Q10. Hāʻawi kēia pūnaewele i ka mana i nāʻiʻo o ke kino a me ka lolo. Me ka nele o ka coenzymes, ua mālamaʻia kēia mau pilikia:
- luhi;
- ka nawaliwali a me ka eha i loko o nāʻiʻo;
- ka piʻiʻana a me nā'ōponaʻoi aku i ke kahe o ke koko;
- ka hōʻoia o ka puʻuwai hauʻoli;
- ka lukuʻana o ke kino o kaʻiʻo (rhabdomyolysis).
Aia kekahi mau meaʻino'ē aʻe e hoʻonāukiukiʻia e nāʻano o statins - pili i:
- nā pilikia hiamoe;
- ka hopena o ka lohe a me ke koi o nā meaʻono;
- ka hoʻemiʻiaʻana o nā helu pāletina i loko o ke koko;
- kahoʻaunuʻa;
- kahe mauʻana o ke koko;
- eha i ka'āpana epigastric;
- ka piʻi pinepine o ka urination;
- nā pilikia keʻokeʻo;
- piʻi nui ka wela;
- ka hewa o ka mana;
- nā hopena maʻi;
- nā mea nui;
- nausea;
- ka maʻi maloʻo;
- 'ōnaeheʻaoʻao;
- Hoʻonuiʻia kaʻili o kaʻili i ka hoʻoulu uila ultraviolet;
- 'ōpala;
- kaʻulaʻula a me ke kaniʻana o ka epidermis;
- flatulence;
- luaʻi;
- ka piʻi pinepineʻana o ka hoʻihoʻiʻana o ka hānō maʻamau;
- nā hopena pilikia;
- ka hōʻehaʻeha o ka lolo;
- nā hoʻololi o ka naʻau;
- kauā;
- pancreatitis;
- nā hoʻomaha;
- ka hoʻonāukiukiʻana o ka maʻi o ka maʻi a me ka maʻi o nā maʻi;
- nā hoʻololi o ka naʻau;
- hauʻoli;
- nāʻeha o ka maʻi nerveʻole inflammatory;
- anorexia;
- luaʻi;
- ka peeling a me ka peeling o nāʻula luna o kaʻili;
- he pīpī;
- ka piʻiʻana o ka hanu koko;
- ka hōʻeha a me ka hoʻonāʻana o nā puʻupaʻa.
He nui nā hopena maikaʻiʻole i loko o nā kūlana palekana, akā, he mea paʻakikī wale nō aʻo ka hapanui o ka poʻe i hahaiʻole i nā kānāwai o ka hoʻohanaʻana i nā lāʻau. Hoʻomaʻoʻia me nā lāʻau lipid-lowering pili i ka hōʻoleʻana i ka waiʻona, ka puhiʻana, ka hana maʻamau a me kaʻai palekana palekana. Inā mālamaʻoe i kēia mau papa, hiki ke pale i nāʻaoʻao o kaʻaoʻao.
Nā hanauna o nā kumukūʻau
ʻO nā mea lapaʻau mua loa i hoʻokaʻawaleʻia mai nā hua maoli. Ma muli o kēia mau pūhui, ua hoʻokumuʻia nā lāʻau o ka lovastatin. ʻO nā mea'ē aʻe i koe a me nā hanauna hou o nā lāʻau lapaʻau i hanaʻia mai nā mea synthetic. He kuhihewa i ka manaʻoʻana o nā'enela kūlohelohe mai ke cholesterol eʻoi aku ka maikaʻi a me ka palekana. ʻAʻole hiki i nā lāʻau lapaʻau ke loaʻa i nā hopena maikaʻiʻole a uaʻoi aku ka maikaʻi. Ma waho aʻe o ka lovastatin,ʻo ka hanauna mua o nā mea i ho'ākākaʻia e komo pū me ka simvastatin a me ka pravastatin.
ʻO nā hopena lipid-downering mua paha e hana i kahi hua'ōlelo. Hoʻohana nuiʻia nā statins maikaʻi i ke kāohiʻana i nāʻeha, ke atherosclerosis, ka'elepopo o ka myocardial, i ka mea nui inā he mau hiʻona kūikawā i nā maʻi i heluʻia. Nā hōʻailona no ka laweʻana i nā lāʻau lalani mua:
- ke keki'keʻa atherosclerosis;
- Ka lawaʻole o kahiʻai i loko o kahi pahu me nā kaumaha kino;
- mua hypercholesterolemia.
ʻO ka lua o nā lāʻau i hoʻohanaʻia i nā lāʻau'awaʻona, he pani wale nō ia. He mau lāʻau lapaʻau kūpono a palekana paha kēia e hiki ke kākauʻia i nā keiki mai ka 10 mau makahiki. Aia lākou i ka paʻakai sodona, no laila, ua emi koke ka manaʻo o ka cholesterol i loko o ke koko. Nā kuhikuhi no ka hoʻohanaʻana i ka fluvastatin:
- dyslipidemia o nāʻano likeʻole;
- ka maʻi o ka maʻi ischemic (e pale i nā pilikia);
- ke keki'keʻa atherosclerosis;
- hypercholesterolemia;
- Ka paleʻana i nā hopena maikaʻiʻole o ka'ōpū a me ke kaukoko.
ʻO ke kolu o ka hanauna o nā lāʻau lipid-lowering atorvastatin. ʻO kaʻano likeʻole o kēia mau lāʻau lapaʻau he mea kūpono i ka holomua o ka'ōnaehana cardiovascular. Manaʻoʻiaʻo nā statins mai ka cholesterol i nā papa hana wikiwiki loa, palekana a palekana no ka paleʻana i ka maʻi diabetes a me nā maʻi o ka maʻi diabetes, e like me ka maʻi maʻamau. Nā hōʻike no ko lākou kumuhana:
- ka predisposition āpau i nā maʻi o ka'ōnaeʻa cardiovascular;
- dyslipidemia i huiʻia;
- kaupaona hypercholesterolemia;
- holomua i ke atherosclerosis.
ʻO nā kūlana o ka hanauna hou loa,ʻo Petervastatin a me ka rosuvastatin. ʻO kēia mau lāʻau lapaʻau kahi mea hou loa i keʻano o ka lāʻau lapaʻau, a uaʻoi aku ko lākou pōmaikaʻi ma luna o ko lākou mau mua:
- ka hopena wikiwiki loa (hiki keʻikeʻia nā hopena mai ka pule mua o ke komoʻana);
- nāʻano lāʻau lapaʻau;
- hana mau;
- ka hopena o nā hopena pili;
- hiki ke hoʻohana pūʻia me nā meaʻimi pūpū;
- ʻaʻohe mea e pili ai i ka metabolism glucose.
ʻO nā kūlana hou o ka cholesterol nā hōʻailona maikaʻi loa a palekana i'ōleloʻia i nā hihia i lalo:
- hypercholesterolemia ma kēlā me kēia manawa;
- holomua, paʻakikī atherosclerosis;
- ka maʻi o ka maʻi ischemic;
- maʻi diabetes ;
- dyslipidemia;
- ka predisposition genetic i nā maʻi o ka maʻi;
- ke ola hou ma hope o ka hōʻeha o ka puʻuwai, ka hahau, ka'ōpū o ke naʻau.
ʻO nā lāʻau hōʻailona - ka papa inoa
ʻO nā lāʻau lapaʻau ma luna o kēlā me kēia hanauna he mau inoa likeʻole. E koho maʻamau i nā lāʻau lapaʻau e hoʻoemi i ka cholesterol i loko o ke koko, hikiʻole iāʻoe. ʻO nā mea hana kūponoʻole, ka helu kūponoʻole,ʻo ka huiʻana me nā hui likeʻole o nā mea hana lāʻau pharmacological hiki ke hoʻoulu i ka hopena o nā hopena hopena weliweli loa a me nā loli hikiʻole ke hoʻololiʻia i loko o ka hana hana o nā moʻo, nā hana hana kūmole. ʻO kahi kauka kauka kūpono wale nō e aʻo i nā lāʻau lapaʻau e hoʻemi i ka cholesterol i loko o ke koko me ka maluhia. ʻO ke kūlana kūpono o nā statin koho i kohoʻia e kekahi mea lapaʻau.
Nā like ana o Simvastatin
Ke kūʻaiʻia kēia waiwai ma keʻano o nā papa o ka inoa like. Ma keʻano he mea hana ikaika, aia ka simvastatin i nā lāʻau lapalapa lipid-lowering - he papa inoa:
- ʻO Simvastol;
- Zovatin;
- ʻo Simgal;
- Zoror;
- Hoʻohuihui;
- Kauka;
- ʻO Simvard;
- Vastatin;
- ʻo Simvakor;
- Ovenkor;
- ʻo Simlo;
- Vazilip;
- Sincard a me nā mea'ē aʻe.
Nā like ana e like me ka Pravastatin
ʻO kēia kekahi meaʻokoʻa maikaʻi a palekana o ka hanauna mua o nā lāʻau lapaʻau lipid-downering. ʻO ka mea hana i ho'ākākaʻia i kākauʻia aia nā lāʻau lapaʻau e ho'ēmi i ka cholesterol i loko o ke koko (statins):
- Hoʻomalu;
- Lipostat;
- ʻO Pravastatin.
Nā like ana lovastatin
ʻO ka lāʻau lapaʻau mua loa, e hoʻokaʻawaleʻia ana mai nā fungi penicillin,ʻaʻoleʻoi aku ka maikaʻi loa, akāʻo kekahi o nā mea palekana loa. Nā lāʻau'alopeka e emi iho ka cholesterol, ma muli o ka lovastatin:
- Holletar;
- Lovacor;
- Kākau Cardiostatin;
- Lovasterol;
- Mevakor;
- Lovastatin;
- Kauxstatin;
- Lovahexal;
- Pā'ālua;
- Rovacor;
- ʻO Liprox a me nā mea'ē aʻe.
Nā like ana o Fluvastatin
ʻO nā kūlana mai kaʻelua o nā hanauna cholesterol i kahi mea hoʻokahi. Ma ke kumu wale nō i huaʻia nā papa - Leskol. Ua kūʻaiʻia lākou i 3 mau paʻi me ka like hoʻokahi (80 mg):
- Lāʻau (Leskol);
- Maka;
- XL.
'Ōlelo Atorvastatin - like ana
ʻO kēia mea pili i nā mea o nā mea pili i ka lāʻau o kaʻekolu o nā hanauna o nā lāʻau lapaʻau. Nā hoʻomākaukauʻana o kahi statin ma ke kumu:
- Lipitor;
- Anistat;
- Liprimar;
- ʻO Atorvastatin;
- Tulip;
- Atomax;
- Canon;
- ʻO Torvacard;
- Atorvox;
- Liptonorm;
- Atoris a me nā mea'ē aʻe.
ʻO nā loinaʻo Rosuvastatin
ʻO nā kumukūʻai no ka ho'ēmiʻana o ka cholesterol mai ka hā o ka hanauna ke kumu hopena maikaʻi loa a me ka hana lōʻihi. ʻO Rosuvastatin,ʻo ia hoʻi me nā papa o ka inoa hoʻokahi, aia i loko o nā lāʻau lapaʻau e like me kēia:
- Mertenil;
- ʻO Rosulip;
- ʻO ke Keʻa;
- ʻO Rosewood;
- Akorta;
- ʻO Rosart;
- ʻO Tevastor;
- ʻO Roxer.
Nā like ana o Petervastatin
Ua hoʻopihaʻia nā lāʻau lapaʻau lipid-downering o ka hā o ka hanauna i ka lāʻau lapaʻau i nīnauʻia i kekahi mau makahiki i hala iho nei. ʻO kēia mau lāʻau mai ka cholesterol ka mea maikaʻi a palekana i waena o nā lāʻau likeʻole. Loaʻa iā lākou ka hopena wikiwiki loa a lōʻihi loa me ka loaʻaʻole o kekahi olakino olakino. Ma muli o Petervastatin, hoʻokahi wale nō koho i ka manawa -ʻo Livazo.
Nā kūlana o ka hanauna hou loa me nā hopena hope loa
Hoʻonaʻauao nā kauka hōʻailona e kākau wale i nā lāʻau lapaʻau ponoʻole me nā kaulike lāʻau lōʻihi a me ka hana lōʻihi. ʻO nāʻoihana kūpono loa o ka cholesterol he rosuvastatin aʻo Petervastatin:
- ʻO ke Keʻa;
- Mertenil;
- Roxer;
- Valarox;
- ʻO Rosáv;
- Akorta;
- ʻO Rosewood;
- Livazo.